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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH1A1
All Species:
27.27
Human Site:
T493
Identified Species:
54.55
UniProt:
P00352
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00352
NP_000680.2
501
54862
T493
Y
T
E
V
K
T
V
T
V
K
I
S
Q
K
N
Chimpanzee
Pan troglodytes
XP_001143226
476
52240
T468
Y
T
E
V
K
T
V
T
V
K
I
S
Q
K
N
Rhesus Macaque
Macaca mulatta
XP_001097512
501
54782
T493
Y
T
E
V
K
T
V
T
V
K
I
S
Q
K
N
Dog
Lupus familis
XP_533525
501
54927
T493
Y
T
E
V
K
M
V
T
M
K
I
S
Q
K
N
Cat
Felis silvestris
Mouse
Mus musculus
P24549
501
54449
A493
Y
T
E
L
K
T
V
A
M
K
I
S
Q
K
N
Rat
Rattus norvegicus
P51647
501
54440
A493
Y
T
E
L
K
T
V
A
M
K
I
S
Q
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506070
601
66397
T593
Y
T
E
V
K
T
V
T
V
K
I
S
E
K
N
Chicken
Gallus gallus
P27463
509
55791
T501
Y
T
E
V
K
T
V
T
I
K
I
P
Q
K
N
Frog
Xenopus laevis
Q6GNL7
902
99964
T895
A
L
N
E
Y
L
K
T
K
A
V
T
I
E
Y
Zebra Danio
Brachydanio rerio
NP_571925
518
56497
T510
Y
T
E
L
K
T
I
T
M
K
M
S
G
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU63
538
58570
V529
Y
L
Q
I
K
A
V
V
T
A
L
N
K
P
A
Baker's Yeast
Sacchar. cerevisiae
P32872
511
56448
R503
N
K
N
S
G
M
G
R
E
L
G
E
Y
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
98.8
89
N.A.
87
86.4
N.A.
72.5
82.5
29.8
70
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95
99.1
95
N.A.
94.4
94
N.A.
79.6
90.3
40.3
81.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
93.3
86.6
6.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
100
93.3
26.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
52.9
60.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
67.8
70.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
9
0
17
0
17
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
75
9
0
0
0
0
9
0
0
9
9
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
9
0
0
0
9
0
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
9
0
9
0
67
0
9
0
0
% I
% Lys:
0
9
0
0
84
0
9
0
9
75
0
0
9
75
0
% K
% Leu:
0
17
0
25
0
9
0
0
0
9
9
0
0
0
9
% L
% Met:
0
0
0
0
0
17
0
0
34
0
9
0
0
0
0
% M
% Asn:
9
0
17
0
0
0
0
0
0
0
0
9
0
0
67
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
59
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
9
0
0
0
0
0
0
0
67
0
0
0
% S
% Thr:
0
75
0
0
0
67
0
67
9
0
0
9
0
0
9
% T
% Val:
0
0
0
50
0
0
75
9
34
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
84
0
0
0
9
0
0
0
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _